Composition and method for topical application to skin, hair and nails

摘要

A composition and method thereof treating or conditioning human skin, hair or nails is described. The composition is topically applied in an effective amount and contains from about 0.0001 to about 50 wt. % of a ceramide derivative containing sphingoid bases having amide, but not ester linkages to a 2 (alpha)-hydroxy carboxylic acid and a safe and effective amount of a pharmaceutical or cosmetically acceptable carrier. The composition effectively treats or conditions areas of fine flakes having histogram values of 10 to 128. Treated areas exhibit a desquamation value difference of 1.0 or greater at day 28 after treatment commences compared to a desquamation value of untreated areas.