发明名称 Preparation of powder agglomerates
摘要 The invention relates to a dosage form of a pharmacologically active agent useful for administration by oral inhalation therapy, comprising agglomerates of particles of a pharmacologically active agent and particles of a crystalline solid binder, said particles having an average particle size of 10 mu m or less, and being provided in a weight ratio of between 100:1 to 1:500 of said first material to said crystalline binder, said agglomerates having an average size of between 400 and 700 mu m, a bulk density of between 0.2 and 0.4 g/cm<3> and a crush strength of between 200 mg and 1,500 mg.
申请公布号 ZA9802254(B) 申请公布日期 1998.09.17
申请号 ZA19980002254 申请日期 1998.03.17
申请人 SCHERING CORPORATION. 发明人 TSONG-TOH YANG
分类号 A61K9/00;A61K9/16;A61K9/72;A61K31/137;A61K31/216;A61K31/27;A61K31/404;A61K31/41;A61K31/42;A61K31/439;A61K31/4704;A61K31/56;A61K31/573;A61K38/21;A61K38/22;A61K38/28;A61K47/26;A61M15/00 主分类号 A61K9/00
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