INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

摘要

A compound which is a 2-(1H-indol-2-yl)-5¢(2H-pyrrol-2-ylidene)methyl!-1H-pyrrole of formula (I), wherein each of R1, R2, R3 and R4 independently represents hydrogen, C1-C6 alkyl, halogen, cyano, nitro, hydroxy, C1-C6 alkoxy unsubstituted or substituted by phenyl, C1-C6 alkyl-carbonyloxy or amino; R5 represents halogen, hydroxy or C1-C11 alkoxy unsubstituted or substituted by phenyl; and R6 represents hydrogen, C2-C20 alkanoyl, C3-C20 alkenoyl, phenyl, C1-C20 alkyl or C2-C20 alkenyl, wherein the alkanoyl, alkenoyl and alkyl groups are unsubstituted or substituted; or a pharmaceutically acceptable salt thereof, is useful as immunomodulating agent and for treating adult-T-cell leukemia-lymphoma.