TRIAZOLE DERIVATIVES, PROCESS OF THEIR PREPARATION AND USE AS WELL AS INTERMEDIATES OF SUCH PROCESS

摘要

The invention provides antifungal agents of the formula:- and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF3; R<1> is C1-C4 alkyl; R<2> is H or C1-C4 alkyl; and "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C1-C4 alkyl, C1-C4 alkoxy, halo, CF3, CN, NO2, NH2, -NH(C1-C4 alkanoyl) or -NHCO2(C1-C4 alkyl).