| 发明名称 |
COMBINATORIAL DIHYDROBENZOPYRAN LIBRARY |
| 摘要 |
<p>Combinatorial libraries are disclosed which are represented by Formula I: wherein: is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula which interact (i.e., as agonists or antagonists) with alpha adrenergic receptors, dopamine receptors, sigma -opiate receptors, and K+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma.</p> |
| 申请公布号 |
EP0864087(A1) |
申请公布日期 |
1998.09.16 |
| 申请号 |
EP19960939617 |
申请日期 |
1996.11.04 |
| 申请人 |
PHARMACOPEIA, INC. |
发明人 |
BALDWIN, JOHN, J.;DILLARD, LAWRENCE, W.;LI, GE;READER, JOHN, C.;ZENG, WENGUANG |
| 分类号 |
G01N33/50;A61K31/353;A61P9/12;A61P11/00;A61P11/06;A61P13/08;A61P25/18;A61P25/24;A61P25/28;A61P27/06;A61P43/00;C07B61/00;C07C201/12;C07C205/59;C07C233/01;C07C237/28;C07C237/42;C07D311/08;C07D311/22;C07D311/58;C07D311/68;C07D311/72;C07D311/96;C07D491/10;C07D491/107;C07D493/10;C07D493/20;C07D495/10;C07D495/20;C07D497/10;C07D497/20;C12Q1/00;C12Q1/527;G01N33/15;G01N33/543;G01N33/566;G01N33/573;(IPC1-7):G01N33/53;G01N33/551;C12Q1/34;G01N33/567;G01N33/553 |
主分类号 |
G01N33/50 |
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