| 发明名称 |
THROMBIN ACTIVATABLE PLASMINOGEN DERIVATIVES |
| 摘要 |
<p>A plasminogen analogue activatable by thrombin to have plasmin activity which contains the cleavage site sequence P4-P3-Pro-Arg-P1'-P2' where P3 is a basic amino acid residue, P4 is a hydrophobic amino acid residue and each of P1' and P2' is independently a non-acidic amino acid residue, said site being cleavable by thrombin between Arg and P1'.</p> |
| 申请公布号 |
EP0666920(B1) |
申请公布日期 |
1998.09.16 |
| 申请号 |
EP19930923634 |
申请日期 |
1993.10.28 |
| 申请人 |
BRITISH BIOTECH PHARMACEUTICALS LIMITED |
发明人 |
GILBERT, RICHARD JAMES,;HUNTER, MICHAEL GEORGE;DAWSON, KEITH MARTYN |
| 分类号 |
C12N15/09;A61K38/00;A61K38/48;A61P7/02;C07H21/04;C07K7/06;C07K7/08;C07K14/47;C12N9/68;C12N15/57;(IPC1-7):C12N15/57;C12N1/19;C12N5/10 |
主分类号 |
C12N15/09 |
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