| 摘要 |
The present invention relates to a nucleoside having the formula: <IMAGE> where R1 is a hydrogen or a protecting group; R2 is a hydrogen or a coupling group; R3 and R4 are each either a hydrogen or an alkyl group, where R3 and R4 can be connected in a ring; R5 is a hydrogen, an alkyl group, or a carboxylic ester group; R6 is a hydrogen, an alkyl group, or a carboxylic ester group; R7 is a hydrogen, a nitro group, a halogen, a cyano group, or an alkyl group, where R7 is attached at either position 4, 5 or 6; and Base is a protected heterocyclic base. Further, the present invention relates to a method of making the nucleoside and a method of oligomer synthesis utilizing the nucleoside.
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