Anti-HBS antibody genes and expression plasmids therefor

摘要

PCT No. PCT/JP93/00396 Sec. 371 Date Apr. 5, 1994 Sec. 102(e) Date Apr. 5, 1994 PCT Filed Mar. 30, 1993 PCT Pub. No. WO93/20205 PCT Pub. Date Oct. 14, 1993The L and H chains of the human anti-HBs antibody can be produced by the genetic recombination techniques to provide the desired human anti-HBs antibody easily on a large scale. The invention relates to nucleotide base sequences coding for the respective polypeptides that constitute the L and H chains of the anti-HBs antibody, expression plasmids containing them, and transformants prepared by transformation with the expression plasmids.