| 发明名称 |
Lipídeos catiônicos para terapia de gene |
| 摘要 |
<p>This invention provides novel cationic lipids, particularly guanidino lipids, and methods for their preparation. Also provided are polyanionic-lipid complexes comprising the lipids of the invention, their preparation and use to deliver biologically active substances, particularly nucleic acids to cells.</p> |
| 申请公布号 |
BR9705117(A) |
申请公布日期 |
1998.09.15 |
| 申请号 |
BR19979705117 |
申请日期 |
1997.10.22 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
JOHN OTTO LINK;JOHN JOSEPH NESTOR, JR.;GARY ALLEN PELTZ;PAULA NANETTE BELLONI;DONALD ROY HIRSCHFELD |
| 分类号 |
C12N15/09;A61K47/46;A61K47/48;C07C237/06;C07C279/14;C07C279/22;C07C279/24;C07C317/44;C07C323/52;C07D233/30;C07H21/00;(IPC1-7):C07C279/04;C07C279/20;C07C279/26;A61K9/127;C07D487/04;C07D403/06 |
主分类号 |
C12N15/09 |
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