Chichibabin aminations of pyridine bases

摘要

PCT No. PCT/US95/08030 Sec. 371 Date Dec. 20, 1996 Sec. 102(e) Date Dec. 20, 1996 PCT Filed Jun. 26, 1995 PCT Pub. No. WO96/00216 PCT Pub. Date Jan. 4, 1996Improved Chichibabin aminations of pyridine bases are described which are conducted under a pressurized gas phase containing ammonia and in the presence of a selected additive which increases the reaction rate, and also in preferred processes favorably alters the isomer ratios and product yields from the aminations while benefiting product workup and recovery as well.