发明名称 |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain |
摘要 |
The present invention concerns methods for diagnosis and treatment of diseases or disorders characterized by abnormal cellular signal transduction involving a newly identified region, herein termed the "APB domain." APB domain binding between proteins is believed to play an important role in signal transduction pathways and, thereby, influence cellular events. Thus, APB mediated activity plays a role in signal transduction pathways and agents modulating APB mediated activity can be used to treat diseases or disorders involving proteins containing APB domains.
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申请公布号 |
US5807989(A) |
申请公布日期 |
1998.09.15 |
申请号 |
US19940363215 |
申请日期 |
1994.12.23 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
MARGOLIS, BENJAMIN LEWIS;SCHLESSINGER, JOSEPH;YAJNIK, VIJAY |
分类号 |
A61K38/00;C07K14/71;(IPC1-7):C07K4/12;C07K5/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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