摘要 |
An in vitro fertilization method comprising culturing mammalian immature oocytes obtained from a mammalian ovary very early in the mammal's menstrual cyc le in an oocyte maturation inhibitor-containing culture, removing the inhibitor and ma turing and fertilizing the oocytes to produce embryos for subsequent uterine-implantati on. The method allows for more convenient, efficacious, safer, less expensive and timely implantation of a plurality of embryos in the uterus to enhance pregnancy succes s rate. Cryopreservation of the immature oocytes offers enhanced benefits Preferably, th e mammal is human and the inhibitor is dbcAMP.
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