COSTIMULATION OF T-CELL PROLIFERATION BY A CHIMERIC BISPECIFIC COSTIMULATORY PROTEIN

摘要

A soluble bispecific fusion protein consisting of: a) a binding domain which recognizes a specific surface molecule on a target cell, covalently linked to b) a domain capable of stimulating T-cell proliferation, can be used for a specific costimulation of a T-cell directed against said target cell.