| 摘要 |
<p>A compound with topical anesthetic properties is incorporated in polymeric material suitable for forming products useful in the medical arts. A hydrophobic anesthetic compound is used which is more soluble in the polymer than in water so that a quantity of anesthetic compound can be stored in solution in the polymer and not be washed out by aqueous bodily fluid. This results in metered diffusion of drug to the local tissue in an amount sufficient to maintain effective anesthesia of the local tissue while avoiding the associated problems of systemic drug delivery. Examples of medical products include anesthetizing cuffs, films or balloons disposed on catheters or tubes; anesthetic (122) coated sutures (120) or the like; adherent anesthetizing bandages, strips or patches, or in the form of an anesthetizing plastisol or foam suitable for topical application. Methods of manufacturing the compound/polymer are also disclosed.</p> |
