发明名称 |
VECTORS AND METHODS FOR EXPRESSION OF MUTANT PROTEINS |
摘要 |
The present invention describes a new shuttle vector permitting the expression of engineered toxin mutants and toxin fusion proteins in Corynebacterium. In addition the invention provides a mutant Pichia pastoris, a method for producing this mutant and a method of expressing engineered toxin mutants and toxin fusion proteins in the mutant form of Pichia pastoris. The invention further provides a mutant Chinese hamster ovary (CHO) cell, a mutant insect cell, a method for producing these mutants and a method of expressing engineered toxin mutants and toxin fusion proteins in the mutant cells.
|
申请公布号 |
CA2283497(A1) |
申请公布日期 |
1998.09.11 |
申请号 |
CA19982283497 |
申请日期 |
1998.03.05 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
NEVILLE, DAVID M. |
分类号 |
C07K14/34;C12N15/77;C12N15/81;(IPC1-7):C12N15/77;A61K47/48;C12N15/85 |
主分类号 |
C07K14/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|