| 发明名称 |
IONIC MOLECULAR CONJUGATES OF BIODEGRADABLE POLYESTERS AND BIOACTIVE POLYPEPTIDES. |
| 摘要 |
Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50 % by weight, of the polypeptide present in the composition is ionically conjugated to the polyester. |
| 申请公布号 |
EP0678018(A4) |
申请公布日期 |
1998.09.09 |
| 申请号 |
EP19940906037 |
申请日期 |
1994.01.05 |
| 申请人 |
KINERTON LIMITED |
发明人 |
SHALABY, SHALABY W.;JACKSON, STEVEN A.;MOREAU, JACQUES-PIERRE |
| 分类号 |
A61K9/16;A61K9/22;A61K9/52;A61K38/00;A61K38/16;A61K47/34;A61K47/48;A61P5/02;C07K7/23;C07K14/655;C07K17/08;C08G63/02;C08G63/08;C08G63/78 |
主分类号 |
A61K9/16 |
| 代理机构 |
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代理人 |
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