发明名称 |
Compositions comprising leukocyte-derived growth factors and methods of administering same to facilitate wound healing |
摘要 |
A gene encoding a leukocyte-derived growth factor (LDGF) has been isolated, cloned and sequenced. LDGF is believed to correspond to a PDGF-like monocyte-derived growth factor with chemotactic activity which is found in human wound fluid. Protease-resistant and other analogues of LDGF, as well as recombinant LDGF of native amino acid sequence, may now be produced by gene expression in transformed hosts.
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申请公布号 |
US5804176(A) |
申请公布日期 |
1998.09.08 |
申请号 |
US19950416500 |
申请日期 |
1995.04.04 |
申请人 |
THE UNIVERSITY OF SOUTH FLORIDA |
发明人 |
GROTENDORST, GARY ROBERT |
分类号 |
A61K38/22;A61K38/00;A61P17/02;A61P43/00;C07K14/00;C07K14/50;C07K14/52;C12N1/21;C12N5/10;C12N15/09;C12N15/19;C12P21/02;C12R1/91;(IPC1-7):A61K38/19;A61K38/18;A61K38/16 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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