发明名称 Bicyclic amino acids
摘要 The invention relates to compounds of formula (I), wherein X, Y, Z, R<1>, R<2>, R<3>, R<4>, R<5>, R<7>, R<8>, R<11>, m and n have the meaning cited in Claim 1, and to their physiologically acceptable salts. Said compounds can be used as integrin inhibitors, specially for prophylaxis and treatment of circulatory diseases, thrombosis, infarcts, coronary heart diseases, arteriosclerosis, osteoporosis, pathological symptoms sustained or propagated by angiogenesis and in tumor therapy.
申请公布号 AU6620698(A) 申请公布日期 1998.09.08
申请号 AU19980066206 申请日期 1998.02.06
申请人 MERCK PATENT G.M.B.H 发明人 BEATE DIEFENBACH;SIMON GOODMAN;JOACHIM MARZ;PETER RADDATZ;FRIEDRICH RIPPMANN;MATTHIAS WIESNER
分类号 A61K31/335;A61K31/357;A61K31/4178;A61K31/535;A61K31/538;A61P7/02;A61P9/00;A61P9/10;A61P19/10;A61P29/00;A61P31/00;A61P35/00;A61P43/00;C07D265/36;C07D319/20;C07D405/12;C07D413/12 主分类号 A61K31/335
代理机构 代理人
主权项
地址