Detection and modulation of the iaps and naip for the diagnosis and treatment ofproliferative disease

摘要

Disclosed are diagnostic and prognostic methods and kits for the detection and treatment of proliferative diseases such as cancer (e.g. ovarian cancer, breast cancer, and lymphoma). Also disclosed are therapeutics for treating proliferative diseases (and methods for identifying such therapeutics) that utilize IAP and NAIP antisense nucleic acid molecules, antibodies which specifically bind IAP and NAIP polypeptides, and compounds that reduce the biological activities of IAP and NAIP polypeptides.