| 发明名称 |
Expression of signal-peptide-free staphylokinases |
| 摘要 |
PCT No. PCT/EP92/02989 Sec. 371 Date Jun. 30, 1994 Sec. 102(e) Date Jun. 30, 1994 PCT Filed Dec. 28, 1992 PCT Pub. No. WO93/13209 PCT Pub. Date Jul. 8, 1993The invention relates to recombinant staphylokinase polypeptides with plasminogen activator effect and to their production and use. The polypeptides are obtained by expression of DNA sequences which are free from signal-peptide-coding regions.
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| 申请公布号 |
US5801037(A) |
申请公布日期 |
1998.09.01 |
| 申请号 |
US19940256261 |
申请日期 |
1994.06.30 |
| 申请人 |
MEDAC GESELLSCHAFT FUER KLINISCHE SPEZIALPRAEPARATE MBH |
发明人 |
BEHNKE, DETLEV;SCHLOTT, BERNHARD;ALBRECHT, SYBILLE;GUEHRS, KARL-HEINZ;HARTMANN, MANFRED |
| 分类号 |
C12N15/02;A61K38/00;A61K38/46;A61K39/00;A61K39/395;C07K1/20;C07K14/195;C07K14/31;C07K14/41;C07K16/00;C07K16/40;C12N1/21;C12N5/10;C12N5/20;C12N9/00;C12N9/52;C12N9/64;C12N15/09;C12N15/58;C12P21/08;C12R1/01;C12R1/91;(IPC1-7):C12N9/52 |
主分类号 |
C12N15/02 |
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