Collagen-like polypeptides and biopolymers and nucleic acids encoding same

摘要

Synthetic biopolymers can be prepared using recombinant DNA technology or chemical synthetic methods which have properties similar to naturally occuring gelatin or collagen. These materials comprises one or more polypeptides having the peptide sequence represented by the formulae: I: {[(Gly Pro Gln)(Gly Pro Glu)4]2}n II: Gly Pro Glu{[(Gly Pro Gln)(Gly Pro Glu)4]2}n III: Gly Pro Xaa1 Gly Leu Xaa2 Gly Pro Arg Gly Pro Pro Gly Ala Ser Gly Ala Pro Gly Pro Glu Gly Phe Gln Gly wherein Xaa1 and Xaa2 are independently the amino acids identified as Met, Ile, His, Lys, Asn, Tyr or Gln, and n is 1 to 25.