发明名称 |
Cyclohexanone extraction of 3-hydroxymethylcephalosporins |
摘要 |
The cephalosporin intermediates, desacetyl 7-glutaryl ACA and desacetyl cephalosporin D, are obtained in the form of a concentrated aqueous solution from an aqueous solution containing said intermediates in less concentrated form by solvent extraction using cyclohexanone followed by back-extraction into water. The concentrated aqueous solution of intermediate is in a form which can be used for economical production of 7-ACA using known procedures.
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申请公布号 |
US5801241(A) |
申请公布日期 |
1998.09.01 |
申请号 |
US19970896377 |
申请日期 |
1997.07.18 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LIM, GARY M. F.;ROUBIE, JOHN M.;AUDIA, VICKI H. |
分类号 |
C07D501/00;C07D501/12;C07D501/28;(IPC1-7):C07D501/28 |
主分类号 |
C07D501/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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