The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
申请公布号
US5800815(A)
申请公布日期
1998.09.01
申请号
US19940202047
申请日期
1994.02.25
申请人
CYTEL CORPORATION
发明人
CHESTNUT, ROBERT W.;POLLEY, MARGARET J.;PAULSON, JAMES C.;JONES, S. TARRAN;SALDANHA, JOSE W.;BENDIG, MARY M.;KRIEGLER, MICHAEL;PEREZ, CARL;BAYER, ROBERT;NUNN, MICHAEL
