发明名称 |
NOVEL COMPOUNDS - DERIVATIVES OF CARBAZOLONE |
摘要 |
The invention relates to carbazolone derivatives of the formula <CHEM> wherein A stands for a group of formula -CH2-R (V), wherein R means a hydroxyl or 2-methyl-1H-imidazol-1-yl group; B represents a group of formula <CHEM> wherein R1 means hydrogen or a methyl or ethyl group; or A and B together form a group of formula <CHEM> wherein R2 means a methyl or ethyl group; or A and B together form a group of formula <CHEM> The above compounds are useful intermediates in the synthesis of ondansetron of formula <CHEM> chemically 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-c arbazol-4-one. The invention further relates to a novel process for the preparation of compounds of the formula (I), wherein A and B are the same as in formula (I). |
申请公布号 |
PL174526(B1) |
申请公布日期 |
1998.08.31 |
申请号 |
PL19930324329 |
申请日期 |
1993.10.13 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT |
发明人 |
BOD PETER;HARSANYI KALMAN;TRISCHLER FERENC;FEKECS EVA;CSEHI ATTILA;HEGEDUS BELA;MERSICH EVA NEE DONAT;SZABO GYORGYI NEE KOMLOSI;HORVATH ERIKA NEE SZIKI |
分类号 |
A61K31/40;A61K31/403;A61K31/415;A61P1/08;C07D209/88;C07D209/96;C07D403/04;C07D403/06;C07D491/10;C07D491/107 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|