发明名称 |
INHIBITION OF MAJOR GROOVE DNA BINDING PROTEINS BY MODIFIED POLYAMIDES |
摘要 |
This invention provides improved polyamides comprising a positive patch for contacting the phosphate backbone or major groove of a DNA molecule. As such, the improved polyamides are capable of inhibiting the function or binding of a DNA-binding protein to a DNA molecule. The improved polyamide provides for more efficient function of the polyamide.
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申请公布号 |
CA2281948(A1) |
申请公布日期 |
1998.08.27 |
申请号 |
CA19982281948 |
申请日期 |
1998.02.13 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
BAIRD, ELDON E.;DERVAN, PETER B. |
分类号 |
A61K38/00;A61K31/415;A61K31/785;A61K38/04;A61K49/00;A61P43/00;C07D207/34;C07D233/90;C07D403/12;C07D403/14;C07K7/02;C08G69/00;C08G69/08;C12N15/09;C12Q1/68;(IPC1-7):C07K7/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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