2,3-DIHYDRO-1,4-BENZODIOXINE-5-YL-PYRERAZINE DERIVATIVES AND SALTS THEREOF

摘要

FIELD: medicine, organic technology. SUBSTANCE: 2,3-dihydro-1,4-benzodioxine-5-yl-pyperazine derivatives have formula I wherein R1 is halogen, lower alkyl or alkoxyl, hydroxyl or cyan group, m=1 or 2, n=0 or 1. A is alkylene chain comprising 2-6 carbon atoms which may be substituted by one or two lowers alkyl groups or by one phenyl group. B is methylene, ethylene, carbonyl, sulfunyl, sulfonyl or sulfur. Proposed compounds or salts thereof posses 5-HT1A-antagonist activity. EFFECT: improved quality of product. 1 tblm