发明名称 |
OLIGONUCLEOTIDES SPECIFIC FOR THE marORAB OPERON |
摘要 |
Disclosed are synthetic oligonucleotides complementary to a transcript of the marORAB operon which inhibit expression of a gene in the operon. Also disclosed are methods of reducing bacterial resistance to antibiotics, and pharmaceutical formulations containing marORAB-specific oligonucleotides of the invention.
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申请公布号 |
WO9837188(A1) |
申请公布日期 |
1998.08.27 |
申请号 |
WO1998US02999 |
申请日期 |
1998.02.20 |
申请人 |
HYBRIDON, INC.;TRUSTEES OF TUFTS COLLEGE |
发明人 |
LEVY, STUART, B.;VON HOFE, ERIC |
分类号 |
C12N15/09;A61K31/18;A61K31/433;A61K31/4409;A61K31/445;A61K31/47;A61K31/496;A61K31/505;A61K31/545;A61K31/65;A61K31/7008;A61K31/7048;A61K31/708;A61K38/00;A61K45/00;A61K48/00;A61P31/04;C12N15/113;C12Q1/68;(IPC1-7):C12N15/11;A61K31/70 |
主分类号 |
C12N15/09 |
代理机构 |
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主权项 |
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地址 |
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