FUNGICIDAL TEST METHOD

摘要

Potential fungicides can be identified by testing compounds in a 3-isopropylmalate dehydrogenase inhibition assay. Also disclosed is the use as a fungicide of a compound which is an inhibitor of 3-isopropylmalate dehydrogenase, mutants of Septoria nodorum disrupted in the 3-isopropylmalate dehydrogenase gene and amino acid sequences, derived from a Septoria nodorum gene coding for the enzyme 3-isopropylmalate dehydrogenase.