发明名称 |
PEPTIDE DETERMINANT ASSOCIATED WITH IMMUNITY |
摘要 |
Novel peptides are provided involving sequences from proteins or interest which include a motif comprising a charged amino acid, followed by two hydrophobic amino acids, followed in the next or succeeding position by a polar amino acid, where the charged or polar amino acid may be substituted by glycine. Peptides having the motif are found to be stimulatory to T-cells and allow for modulation of immune response, as illustrated by tolerizing the host to neurological proteins.
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申请公布号 |
CA1340012(C) |
申请公布日期 |
1998.08.25 |
申请号 |
CA19880574902 |
申请日期 |
1988.08.16 |
申请人 |
TRUSTEES OF LELAND STANFORD JR. UNIVERSITY |
发明人 |
ZAMVIL, SCOTT;STEINMAN, LAWRENCE |
分类号 |
A61K35/14;A61K38/00;A61K39/00;A61P35/00;A61P37/00;C07K14/47;C07K14/705;(IPC1-7):C07K7/08;C07K7/06 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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