IRRADIATION OF BLOOD PRODUCTS

摘要

A thin film (10) or layer (10) of white blood cells, such as the contaminating w hite cells in a platelet concentrate, is irradiated with ultraviolet radiation predominantely of a wavelength of 280 to 320 nanomet ers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so processed substantially lose their capabilit y to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat (10), flexible bag (10) made of poly(ethylene-vinyl acetate) plastic, with the flat (10), flexible bag (10) being stretched in a dir ection normal to the path of ultraviolet radiation. Novel irradiating devices (40) are also disclosed.