发明名称 Alpha-azacyclomethyl benzothiophene and alpha-azacyclomethyl benzofurane derivatives, preparation and therapeutic application
摘要 The invention concerns compounds of formula (I) in which A represents either a hydrogen atom or a hydroxyl group, R1, R2, R4, identical or different, each represent a hydrogen atom, a halogen such as fluorine, chlorine or bromine, a cyano group, a C1-6 alkyl group, a C2-6 alkenyl group, a C3-6 cycloalkyl group, a C3-6 cycloalkenyl group, a C6-14 aryl, a C1-6 alcoxycarbonyl group, a C1-6 hydroxyalkyl group, a C1-6 alcoxy group, a C1-6 alcoxyalkyl group, a C1-6 fluoroalkyl group, a C1-2 perfluoroalkyl group, or R1 and R2 together form, with the benzothiophene or benzofurane carbons bearing R1 and R2, a phenyl; R3 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C1-6 fluoroalkyl group, a C1-2 perfluoroalkyl group, C3-6 cycloalkyl group, C3-6 cycloalkenyl group, a phenyl or a benzyl, a C1-6 alcoxycarbonyl group; R5 represents a hydrogen atom or a halogen such as fluorine, chlorine or bromine; and n represents a whole number from 1 to 6. The invention is applicable in therapy.
申请公布号 AU6218598(A) 申请公布日期 1998.08.25
申请号 AU19980062185 申请日期 1998.01.27
申请人 SYNTHELABO 发明人 CHRISTOPHE PHILIPPO;STEPHANIE AUBOUSSIER;OLIVIER CRESPIN;PHILIPPE BOVY;GILLES COURTEMANCHE
分类号 C07D405/06;C07D409/06 主分类号 C07D405/06
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