Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase

摘要

The subject invention provides Sia alpha 2,3 Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase and an enzymatically active fragment thereof, and a nucleotide sequence encoding said sialyltransferase. The subject invention also provides an extracellularly releasable protein capable of catalyzing Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransfer which comprises the enzymatically active fragment of the Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase together with a signal peptide.