Quinoline-3-carboxamides, their manufacture and use

摘要

Quinoline-3-carboxamides I <IMAGE> (I) where R1 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, and the organic radicals may be substituted or unsubstituted; R2 is hydrogen, hydroxyl, alkoxy, alkenyloxy, dialkylamino, alkyl, alkenyl, alkynyl, cycloalkyl, and the organic radicals may be substituted or unsubstituted; or R1, R2 together denote an alkylene chain of 4 to 7 members and which may be interrupted by oxygen, sulfur or N-methyl; R3-R6 are hydrogen, alkyl, alkoxy, haloalkyl, haloalkoxy, alkylthio, haloalkylthio, halogen, cyano or nitro; X is oxygen or sulfur; with the proviso that R2 is not hydrogen, C1-C3-alkyl, n-butyl, 3-methylbutyl, cyclohexyl, hexyl, heptyl, octyl, 2-chlorobenzyl, 3-(dimethylamino)propyl, 3-(diethylamino)propyl, 2-morpholinoethyl or 2-(3,4-dimethoxyphenyl)ethyl when R1 and R3 to R6 are hydrogen and X is oxygen, and that R2 is not benzyl when R1 is methyl, R3 to R6 are hydrogen and X is oxygen, and that R1 and R2 do not jointly denote morpholino when R3 to R6 are hydrogen and X is oxygen.