发明名称 Amino acid derivatives
摘要 A novel amino acid derivative represented by the general formula (I) shown below or a salt thereof have now been provided by chemical synthesis, and it has been found that these new compounds stimulate proliferation and physiological activities of the T cells of mammals, have an immunomodulating activity and also have an antitumor activity or a carcinostatic activity. It has also been found that these new compounds have an effect of stimulating the proliferation of hematopoietic stem cells. <IMAGE> (I) wherein y is 0 or 1; R1 represents an unsubstituted C1-C8 alkyl group or others; R2 represents a hydrogen atom, a C1-C5 alkyl group or others; R3 represents a hydrogen atom, a C1-C8 alkyl group or others; R4 represents a hydrogen atom, a C1-C3 alkyl group or others; R5 represents a group -OR42, a group <IMAGE> or others.
申请公布号 US5798387(A) 申请公布日期 1998.08.25
申请号 US19960753381 申请日期 1996.11.25
申请人 ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI;KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA 发明人 ISHIZUKA, MASAAKI;KAWAZU, MASAJI;KATSUMI, TOSHIAKI;FUSE, YOSHIHIDE;MAEDA, KENJI;TAKEUCHI, TOMIO
分类号 C07C233/47;C07C235/12;C07C237/12;C07C323/59;(IPC1-7):A61K31/22 主分类号 C07C233/47
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