发明名称 Piperazino derivatives as neurokinin antagonists
摘要 The invention relates to compounds of the formulas <IMAGE> I wherein Z, Rc, y, x, l1, l2, l3, u, R4, Rc', n, R1, R2, and R3, are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
申请公布号 US5798359(A) 申请公布日期 1998.08.25
申请号 US19950451113 申请日期 1995.05.25
申请人 SCHERING CORPORATION 发明人 SHUE, HO-JANE;SHIH, NENG-YANG;PIWINSKI, JOHN;CHEN, XIAO;BLYTHIN, DAVID J.
分类号 C07D241/04;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D453/02;C07D487/04;C07D487/10;(IPC1-7):A61K31/495;A61K31/395;C07D401/00;C07D403/00 主分类号 C07D241/04
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