| 发明名称 |
Recombinant mutant thrombin |
| 摘要 |
Proteolytically inactive thrombin mutated at positions 43 and/or 99 and/or 205, whereby said mutation renders thrombin an antagonist of thrombin receptor.
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| 申请公布号 |
US5798248(A) |
申请公布日期 |
1998.08.25 |
| 申请号 |
US19950485886 |
申请日期 |
1995.06.07 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
COUGHLIN, SHAUN R.;SCARBOROUGH, ROBERT M. |
| 分类号 |
A61K38/00;A61K39/00;A61K39/395;A61K49/00;A61P7/02;A61P9/08;A61P9/10;A61P43/00;C07K7/02;C07K7/06;C07K14/705;C07K16/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/74;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12R1/19;G01N33/53;(IPC1-7):C12N9/74;C12N1/20;C07H21/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
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