发明名称 |
ALKIN-DERIVATE UND VERFAHREN ZU IHRER HERSTELLUNG |
摘要 |
Alkyne compounds of the formula <IMAGE> wherein R1 is H, alkyl of up to 4 carbon atoms or phenyl; R2 is H, aliphatic acyl of up to 6 carbon atoms or aroyl of up to 11 carbon atoms; R3 and R4 are H, F, Cl or Br and n is 0 or 1, and physiologicaly acceptable metals salts thereof, have antiinflammatory activity. These compounds can be made from compounds of the formula <IMAGE> wherein Q is a functionally-modified hydroxy and R1, R3, R4 and n are as above by treatment with a solvolyzing agent. |
申请公布号 |
DE2527352(A1) |
申请公布日期 |
1976.12.30 |
申请号 |
DE19752527352 |
申请日期 |
1975.06.19 |
申请人 |
MERCK PATENT GMBH |
发明人 |
GANTE,JOACHIM,DR.;KURMEIER,HANS-ADOLF,DR.;ORTH,DIETER,DR.;SCHACHT,ERICH,DR.;WILD,ALBRECHT,PROF.DR. |
分类号 |
C07C69/007;A61K31/065;A61K31/085;A61K31/215;A61K31/22;A61P3/06;A61P7/02;A61P25/04;A61P29/00;C07C27/00;C07C29/42;C07C33/28;C07C33/48;C07C41/00;C07C43/295;C07C67/00;C07C69/145;C07F1/00 |
主分类号 |
C07C69/007 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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