发明名称 5-AMINOALKOXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES BEING DOPAMINE AGONISTS
摘要 This invention relates to compounds of Formula (I) wherein: R1 and R2 are independently selected from hydrogen, straight-chain and branched alkyl group having up to 10 carbon atoms or -(CH2)mAr where Ar is phenyl, naphthyl or thienyl, each optionally substituted by one or two substituents selected independently from C1-C6 alkyl, halogen, C1-C6 alkoxide and trifluoromethyl; or NR1R2 is 1,2,3,4-tetrahydroquinolin-1-yl or 1,2,3,4-tetrahydroisoquinolin-2-yl; m is 1-5; n is 1 or 2; Y is halogen, C1-C6 alkyl, and C1-C6 alkoxy; or the pharmaceutically acceptalbe salts thereof, which are dopamine D2 agonists and therefore useful in the treatment of psychoses and Parkinson's disease.
申请公布号 CA2278757(A1) 申请公布日期 1998.08.20
申请号 CA19982278757 申请日期 1998.01.13
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 NELSON, JAMES ALBERT;SHAH, URESH SHANTILAL;MEWSHAW, RICHARD ERIC
分类号 A61K31/502;A61P25/16;A61P25/18;A61P43/00;C07D241/44;C07D401/12;(IPC1-7):C07D241/44;A61K31/47 主分类号 A61K31/502
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