发明名称 NEURTURIN RECEPTOR
摘要 NTNR alpha , NTNR alpha extracellular domain (ECD), NTNR alpha variants, chimeric NTNR alpha (e.g., NTNR alpha immunoadhesion), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described, including methods to modulate cell activity and survival by response to NTNR alpha -ligands, for example NTN, by providing NTNR alpha to the cell.
申请公布号 WO9836072(A1) 申请公布日期 1998.08.20
申请号 WO1998US03179 申请日期 1998.02.17
申请人 GENENTECH, INC. 发明人 KLEIN, ROBERT, D.;ROSENTHAL, ARNON;HYNES, MARY, A.
分类号 A01K67/027;A61K38/00;A61K39/395;A61P25/16;C07K1/22;C07K14/71;C07K16/28;C07K16/46;C07K19/00;C12N5/10;C12N15/09;C12N15/12;C12P21/08;G01N33/53;(IPC1-7):C12N15/12;G01N33/68;A61K38/17;C12N15/85 主分类号 A01K67/027
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