3'-N-OXIDE, 3'-N-DIMETHYLAMINE, 9-OXIME ERYTHROMYCIN A DERIVATIVES

摘要

The disclosed invention relates to novel 3'-N-O, 9-O-oxime protected, 6-O-alkyl erythromycin derivatives of formula (I), a process of preparing the same. The invention also relates to a process of preparing 6-O-alkyl erythromycin A by eliminating the 3'-N-oxide group and 9-O-oxime protecting groups and optionally deprotecting the hydroxy groups at the 2'- and 4''positions under suitable reaction conditions.