Methods for forming combinatorial libraries and the libraries produced thereby are provided. According to a preferred aspect of the invention, a plurality of core molecules are reacted with a plurality of different tool molecules to form a library of molecules having non-naturally occurring molecular diversity. The libraries are useful for identifying lead compounds which modulate the functional activity of a biological molecule.
申请公布号
WO9835923(A1)
申请公布日期
1998.08.20
申请号
WO1998US02812
申请日期
1998.02.13
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;REBEK, JULIUS, JR.;CARELL, THOMAS;WINTNER, EDWARD, A.
发明人
REBEK, JULIUS, JR.;CARELL, THOMAS;WINTNER, EDWARD, A.