发明名称 |
IL-12 GENE EXPRESSION AND DELIVERY SYSTEMS AND USES |
摘要 |
Plasmid expression systems for delivery of DNA coding sequences to a mammal are described which provide expression of multiple coding sequences from a single plasmid. Also described are particular lipid/DNA delivery systems having advantageous characteristics of size, charge ratio, and proportion of supercoiled DNA, and methods of preparing and using such delivery systems for treatment. |
申请公布号 |
WO9817689(A3) |
申请公布日期 |
1998.08.20 |
申请号 |
WO1997US18779 |
申请日期 |
1997.10.10 |
申请人 |
GENEMEDICINE, INC.;NORDSTROM, JEFF;FREIMARK, BRUCE;DESHPANDE, DEEPA |
发明人 |
NORDSTROM, JEFF;FREIMARK, BRUCE;DESHPANDE, DEEPA |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K47/18;A61K47/28;A61K48/00;A61P11/06;C07K14/54;C12N15/24 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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