发明名称 Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl) pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)-amide, a process for the preparation thereof, the use thereof as pharmaceuticals and starting materials
摘要 Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)amide, a process for the preparation thereof, the use thereof as pharmaceuticals and starting materials. Salts, which are soluble and freely soluble in water, of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)-amide and a process for the preparation thereof are described. The compounds are suitable for the treatment of lipid metabolism disorders which are beneficially influenced by stimulation of the hepatic LDL receptor. Also described are the compounds of the formula IV <IMAGE> IV and the salts thereof.
申请公布号 US5795899(A) 申请公布日期 1998.08.18
申请号 US19950394521 申请日期 1995.02.23
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 KAMPE, KLAUS-DIETER;GRANZER, ERNOLD;LEINEWEBER, MICHAEL;HUETTINGER, MANFRED
分类号 A61K31/505;A61K31/506;A61P3/00;A61P3/06;C07D233/36;C07D233/38;C07D403/04;(IPC1-7):C07D403/02 主分类号 A61K31/505
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