| 摘要 |
PCT No. PCT/US95/10945 Sec. 371 Date Feb. 11, 1997 Sec. 102(e) Date Feb. 11, 1997 PCT Filed Aug. 30, 1995 PCT Pub. No. WO96/06606 PCT Pub. Date Mar. 7, 1996Compounds having general formula (I) wherein R is hydrogen or C1-C10 alkyl; X is an aromatic moiety selected from phenyl, thienyl, furyl, pyridyl, imidazolyl, benzimidazolyl, benzothiazolyl and phthalazinyl which is unsubstituted or substituted with one or more moieties chosen from the group consisting of halogen, hydroxy, cyano, nitro, C1-C6 alkyl, C3-C6 cycloalkyl, C1-C4 alkoxy, carboxy, C1-C6 alkoxycarbonyl, acetyl, formyl, carboxymethyl, hydroxymethyl, amino, aminomethyl, methylenedioxy and trifluoromethyl; and "Aryl" represents p-nitrophenyl, p-aminophenyl or p-(protected amino) phenyl; or a pharmaceutically acceptable salt thereof, are useful as anticonvulsants.
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