Gastin and CCK receptor ligands

摘要

PCT No. PCT/GB94/01741 Sec. 371 Date Mar. 18, 1996 Sec. 102(e) Date Mar. 18, 1996 PCT Filed Aug. 9, 1994 PCT Pub. No. WO95/04720 PCT Pub. Date Feb. 16, 1995Compounds of formula (Ia), (Ib), or (Ic), wherein A represents a group having two fused rings, or a group of formula (Id), R1(m) represents up to 6 substituents, K represents -O-, -S-, -CH2-, -N(R2)- or -N(COR2)-, in which R2 is H or C1 to C3 alkyl, W is a carbonyl, sulfonyl or sulfinyl group, provided that at least one of W and X contains carbonyl, Y and Z are as given in the description, and their pharmaceutically acceptable salts are ligands at CCK and/or gastrin receptors. <IMAGE> (Ia) <IMAGE> (Ib) <IMAGE> (Ic) <IMAGE> (Id)