发明名称 |
Group B streptococcus type V polysaccharide-protein conjugate vaccines |
摘要 |
This invention relates to antigenic conjugate molecules comprising the capsular polysaccharide of Group B streptococcus type II which are covalently linked to protein. This invention further relates to antigenic conjugate molecules comprising the capsular polysaccharide of Group B streptococcus type V which are covalently linked to protein. This invention also relates to vaccines and methods of immunizing mammals, including humans against infection by Group B streptococcus type II (GBS II) and/or Group B streptococcus type V (GBS V). Multivalent vaccines comprising the conjugate molecules of this invention and antigens to other pathogenic bacteria are also claimed.
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申请公布号 |
US5795580(A) |
申请公布日期 |
1998.08.18 |
申请号 |
US19950483647 |
申请日期 |
1995.06.07 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA;BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
JENNINGS, HAROLD J.;KASPER, DENNIS L. |
分类号 |
A61K39/09;A61K;A61K39/102;A61K39/108;A61K39/116;A61K39/385;A61K47/48;A61P3/10;A61P31/04;A61P35/00;A61P37/04;C07K14/315;C12P21/00;(IPC1-7):A01J21/00;A01J17/00;C07K1/00 |
主分类号 |
A61K39/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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