| 发明名称 |
High affinity nucleic acid ligands of ICP4 |
| 摘要 |
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to Transcripion Regulatory Factors, specifically ICP4. Included in the invention are specific ssDNA and RNA ligands to ICP4 identified by the SELEX method.
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| 申请公布号 |
US5795721(A) |
申请公布日期 |
1998.08.18 |
| 申请号 |
US19960591989 |
申请日期 |
1996.01.25 |
| 申请人 |
NEXSTAR PHARMACEUTICALS, INC. |
发明人 |
RABIN, ROSS S.;JAYASENA, SUMEDHA D.;GOLD, LARRY |
| 分类号 |
A61K31/70;C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07H21/02;C07H21/04;C07K5/00;C07K14/00;C12N9/12;C12N15/10;C12N15/115;C12P19/34;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):C12Q1/68;G01N33/566 |
主分类号 |
A61K31/70 |
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