COMPLEXE NON-COVALENT COMPRENANT AU MOINS UN ANTICORPS ET UN ELEMENT DE LIAISON AUX IMMUNOGLOBULINES ASSOCIE A UNE SUBSTANCE ACTIVE, SON PROCEDE DE PREPARATION ET SES APPLICATIONS

摘要

The invention concerns a non-covalent complex comprising at least an antibody or an antibody fragment capable of binding with a molecule expressed at a cell surface and an element binding with immunoglobulins (Igs), associated with an active substance, said complex having a specific affinity for appropriate target cells. The invention also concerns said complexes and their applications. Said non-covalent complex comprises (i) at least an antibody or an antibody fragment capable of being bound with a molecule expressed at a cell surface and (ii) an element binding with immunoglobulins, associated with an active substance, said binding element can only be bound with a single type of site on the immunoglobulin.