摘要 |
The invention relates to a transdermal therapeutic system containing active ingredients, comprising a non-adhesive back layer, a reservoir layer containing active ingredients and a self-adhesive surface layer facing the skin, which possibly has a detachable protective layer. Said therapeutic system is characterized in that it has an elastic, or plastically extendible, diffusible back layer with a metal coating, in particular one made of vaporized metal, formed by layer growth, which serves as a permeable barrier for active ingredients and additives contained in the reservoir layer.
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