发明名称 |
ELECTROCHEMICAL PROBES FOR DETECTION OF MOLECULAR INTERACTIONS AND DRUG DISCOVERY |
摘要 |
This invention relates to methods and apparatus for performing electrochemical analyses. The invention provides an electrochemical apparatus for performing potentiometric analyses for detecting specific binding between a first member of a biological binding pair immobilized on an electrode and a second member of a biological binding pair that is electrochemically labeled, in the presence of an electrochemical mediator. Methods for using the apparatus of the invention for performing binding and competition binding assays are provided. The invention also provides methods for performing high throughput screening assays for detecting inhibition of specific binding between the members of the biological binding pair for use in drug development, biochemical analysis and protein purification assays.
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申请公布号 |
CA2279571(A1) |
申请公布日期 |
1998.08.13 |
申请号 |
CA19982279571 |
申请日期 |
1998.02.06 |
申请人 |
XANTHON, INC.;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
FOWLKES, DANA M.;THORP, H. HOLDEN |
分类号 |
G01N33/483;C12Q1/00;G01N27/327;G01N33/543;(IPC1-7):C07K7/08;C07K17/00;G01N27/26;G01N33/53 |
主分类号 |
G01N33/483 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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